Les anglonautes

About | Search | Grammar | Vocapedia | Learning | Docs | Stats | History | News podcasts - Videos | Arts | Science | Translate

 Previous Home Up Next

 

Vocapedia > Health > Genetics > Gene therapy / editing > CRISPR

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Crispr-Cas9 explained: the biggest revolution in gene editing        G        28 March 2019

 

 

 

 

Crispr-Cas9 explained: the biggest revolution in gene editing        The Guardian        28 March 2019

 

Professor Jennifer Doudna,

one the pioneers of Crispr-Cas9 gene editing

explains how this important discovery

enables precise changes to our DNA,

which can be used to correct mutations that cause genetic disease

and completely eradicate it from a germline.

 

Doudna raises the 4 key issues of debate

around this revolutionary discovery

and suggests what will have the most immediate impact.

 

YouTube

https://www.youtube.com/
watch?time_continue=261&v=_PU5bCflzEM
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Biologist Explains One Concept in 5 Levels of Difficulty - CRISPR        WIRED        24 May 2017

 

 

 

 

Biologist Explains One Concept in 5 Levels of Difficulty - CRISPR | WIRED        24 May 2017

YouTube

https://www.youtube.com/watch?v=sweN8d4_MUg

 

 

 

 

 

 

 

 

 

 

 

 

 

 

biotechnology breakthrough > gene-editing technology > Crispr-Cas9

 

CRISPR,

which stands for Clustered Regularly

Interspaced Short Palindromic Repeats,

is the basis

for a revolutionary

genome-editing technology

that allows researchers to make

very precise modifications to DNA.

http://www.npr.org/sections/13.7/2017/06/05/
531537611/crispr-five-ways

 

 

The CRISPR-cas9 technology

allows scientists

to make precise edits in DNA,

and that ability could lead

to whole new medical therapies,

research tools

and even new crop varieties.

http://www.npr.org/sections/health-shots/2016/12/05/
504454201/scientists-battle-in-court-over-lucrative-patents-for-gene-editing-tool

 

 

While everyone welcomes

Crispr-Cas9

as a strategy to treat disease,

many scientists are worried

that it could also be used

to alter genes in human embryos,

sperm or eggs

in ways that can be passed

from generation to generation.

 

The prospect raises fears

of a dystopian future

in which scientists create

an elite population of designer babies

with enhanced intelligence,

beauty or other traits.

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

 

https://www.npr.org/sections/health-shots/2019/07/29/
744826505/sickle-cell-patient-reveals-why-she-is-volunteering-for-landmark-gene-editing-st

 

https://www.npr.org/sections/health-shots/2019/05/22/
723582726/scientists-modify-viruses-with-crispr-to-create-new-weapon-against-superbugs

 

https://www.npr.org/sections/health-shots/2019/04/17/
714121698/gene-therapy-advances-to-better-treat-bubble-boy-disease

 

https://www.npr.org/sections/health-shots/2019/04/16/
712402435/first-u-s-patients-treated-with-crispr-as-gene-editing-human-trials-get-underway

 

https://www.theguardian.com/science/video/2019/mar/28/
the-biggest-revolution-in-gene-editing-crispr-cas9-explained-video

 

https://www.theguardian.com/science/2019/mar/13/
scientists-call-for-global-moratorium-on-crispr-gene-editing

 

https://www.theguardian.com/science/2019/mar/02/
nessa-carey-interview-china-gene-editing-big-pharma-100000-genomes-project

 

https://www.npr.org/sections/health-shots/2019/02/01/
689623550/new-u-s-experiments-aim-to-create-gene-edited-human-embryos

 

 

 

 

https://www.npr.org/sections/health-shots/2018/12/07/
673878474/outrage-intensifies-over-claims-of-gene-edited-babies

 

https://www.nytimes.com/2018/12/05/
health/crispr-gene-editing-embryos.html

 

https://www.npr.org/sections/health-shots/2018/11/26/
670752865/chinese-scientist-says-hes-first-to-genetically-edit-babies

 

https://www.npr.org/sections/health-shots/2018/02/21/
585336506/doctors-in-china-lead-race-to-treat-cancer-by-editing-genes

 

 

 

 

https://www.npr.org/sections/health-shots/2017/12/20/
571208704/scientists-use-gene-editing-to-prevents-a-form-of-deafness-in-mice

 

http://www.npr.org/sections/13.7/2017/06/05/
531537611/crispr-five-ways

 

http://www.npr.org/sections/alltechconsidered/2017/05/27/
530210657/how-a-gene-editing-tool-went-from-labs-to-a-middle-school-classroom

 

http://www.npr.org/sections/health-shots/2017/02/15/
515459773/broad-institute-wins-big-battle-over-crispr-gene-editing-patent

 

 

 

 

http://www.npr.org/sections/health-shots/2016/12/05/
504454201/scientists-battle-in-court-over-lucrative-patents-for-gene-editing-tool

 

http://www.npr.org/sections/health-shots/2016/11/02/
500331130/science-rewards-eureka-moments-except-when-it-doesnt

 

 

 

 

http://www.nytimes.com/2015/12/04/
science/crispr-cas9-human-genome-editing-moratorium.html

 

http://www.nytimes.com/2015/11/15/
magazine/the-crispr-quandary.html

 

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

 

 

 

 

 

 

CRISPR gene-editing tool        USA

 

https://www.npr.org/sections/health-shots/2019/02/01/
689623550/new-u-s-experiments-aim-to-create-gene-edited-human-embryos

 

 

 

 

 

 

 

biotechnology breakthrough > gene-editing technology > gene-edited babies        USA

 

https://www.npr.org/sections/health-shots/2018/12/07/
673878474/outrage-intensifies-over-claims-of-gene-edited-babies

 

 

 

 

 

 

 

create genetically modified babies using CRISPR        USA

 

https://www.npr.org/sections/health-shots/2018/11/26/
670752865/chinese-scientist-says-hes-first-to-genetically-edit-babies

 

 

 

 

 

 

 

create gene-edited human embryos        USA

 

https://www.npr.org/sections/health-shots/2019/02/01/
689623550/new-u-s-experiments-aim-to-create-gene-edited-human-embryos

 

 

 

 

 

 

 

Jennifer A. Doudna

 

biochemist

at the University of California, Berkeley

(who) helped make one

of the most monumental

discoveries in biology:

 

a relatively easy way

to alter any organism’s DNA,

just as a computer user

can edit a word in a document.

 

The discovery

has turned Dr. Doudna

(the first syllable rhymes with loud)

into a celebrity of sorts,

the recipient of numerous

accolades and prizes.

 

The so-called

Crispr-Cas9

genome editing technique

is already widely used

in laboratory studies,

and scientists hope it may one day help

rewrite flawed genes in people,

opening tremendous new possibilities

for treating, even curing, diseases.

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

 

http://www.nytimes.com/2015/11/15/
magazine/the-crispr-quandary.html

 

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

 

 

 

 

 

 

editing the human genome / genome editing

 

Genome editing

is a powerful procedure

that has already been

a game-changer

in helping scientists

to understand the roles of genes

in health and diseases.

 

It coopts

the natural immune defences of bacteria

to create what is often described

as “molecular scissors”.

 

These can cut out,

but also replace,

strands of DNA

with great precision.

 

It is possible to change

single letters of the DNA code.

http://www.theguardian.com/science/2015/sep/02/
genome-editing-how-to-modify-genetic-faults-and-the-human-germline

 

 

http://www.nytimes.com/2015/12/04/
science/crispr-cas9-human-genome-editing-moratorium.html

 

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

http://www.theguardian.com/science/2015/sep/02/
genome-editing-how-to-modify-genetic-faults-and-the-human-germline

 

https://www.youtube.com/watch?v=-sU2HrmZ-7s - 18 August 2015

 

http://www.nytimes.com/2015/05/12/
science/jennifer-doudna-crispr-cas9-genetic-engineering.html

 

http://www.npr.org/blogs/health/2015/03/20/
394311141/scientists-urge-temporary-moratorium-on-human-genome-edits

 

http://www.nytimes.com/2015/03/20/
science/biologists-call-for-halt-to-gene-editing-technique-in-humans.html

 

 

 

 

 

 

 

Related > Anglonautes > Vocapedia

 

genetics

 

 

body, health, medicine, drugs,

viruses, bacteria, diseases,

disability, health care / insurance

 

 

mental health / psychology

 

 

health, life, aging, death

 

 

USA > prescription opioid painkillers

 

 

lifestyle / health > smoking, alcohol, diet, obesity