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Vocapedia > Health > Genetics > Gene therapy / editing

 

 

 

 

Ethics of Genome Editing. Questions on Medical Treatments and the Impact on Future Generations        Video        UNESCO        20 October 2020

 

Is genome editing for medical treatments already available?

What kind of diseases could be cured? How much does it cost? Who can receive such treatments?

Is it OK to modify the genomes of future babies? Who should decide and how?

YouTube

https://www.youtube.com/watch?v=a2wd8jqW5fM

 

 

 

 

 

 

 

 

 

 

 

 

 

 

How gene editing is helping fight disease        BBC        3 December 2015

 

 

 

 

How gene editing is helping fight disease        Video        BBC News        3 December 2015

 

Gene editing - the ability to manipulate our DNA -

is set to transform the way we battle disease.

 

It offers the hope that inherited genetic conditions

could be treated, and perhaps even cured.

 

Scientists from all over the world

have gathered in Washington

to discuss the potential of the technique.

 

Fergus Walsh reports.

 

YouTube

https://www.youtube.com/watch?v=bfqLD7iTR0U

 

 

 

 

 

 

 

 

 

 

 

 

 

Human Genome Editing: Hopes and Fears        WoodrowWilsonCenter        18 August 2015

 

 

 

 

Human Genome Editing: Hopes and Fears        Video        WoodrowWilsonCenter        18 August 2015

 

Breakthroughs in the process of editing the human genome

have scientists both "excited and terrified."

 

What are the potential benefits and risks

associated with altering human DNA

and is science and society

prepared for the ethical, moral,

and policy questions raised

by new technological capabilities?

 

Public Policy Scholar Eleonore Pauwels helps us consider

the implications of controlling the biological process

in this edition of Wilson Center NOW.

 

WoodrowWilsonCenter

https://www.youtube.com/watch?v=-sU2HrmZ-7s

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

DNA > Species-wide Gene Editing > Gene drive        USA

 

A revolutionary technology

known as “gene drive”

(...)  for the first time gives humans

the power to alter or perhaps eliminate

entire populations of organisms in the wild

http://www.nytimes.com/2016/06/09/
science/national-academies-sciences-gene-drive-technology.html

 

http://www.nytimes.com/2016/06/09/
science/national-academies-sciences-gene-drive-technology.html

http://www.npr.org/sections/health-shots/2016/06/08/
481234642/new-genetic-engineering-method-called-promising-and-perilous

 

http://www.nytimes.com/2015/12/22/
science/gene-drives-offer-new-hope-against-diseases-and-crop-pests.html

http://www.npr.org/sections/health-shots/2015/11/05/
451216596/powerful-gene-drive-can-quickly-change-an-entire-species

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

edit

 

 

 

 

 

 

 

 

manipulate genes

 

 

 

 

 

 

 

delete

 

 

 

 

 

 

cut

 

 

 

 

 

 

 

remove

 

 

 

 

 

 

 

repair / fix

 

 

 

 

 

 

 

editing heritable human genes        USA

 

http://www.npr.org/sections/health-shots/2017/02/14/
514580162/scientific-panel-says-editing-heritable-human-genes-could-be-ok-in-the-future

 

 

 

 

 

edit DNA        USA

 

http://www.npr.org/sections/health-shots/2017/08/02/
540975224/scientists-precisely-edit-dna-in-human-embryos-to-fix-a-disease-gene

 

http://www.nytimes.com/2014/03/04/
health/a-powerful-new-way-to-edit-dna.html

 

 

 

 

 

 

 

edit DNA > technique > prime editing        USA

 

https://www.npr.org/sections/health-shots/2019/10/21/
771266879/scientists-create-new-more-powerful-technique-to-edit-genes

 

 

 

 

 

 

 

treat cancer by editing genes        USA

 

https://www.npr.org/sections/health-shots/2018/02/21/
585336506/doctors-in-china-lead-race-to-treat-cancer-by-editing-genes

 

 

 

 

 

 

 

gene therapy > CAR-T cancer therapy        USA

 

https://www.npr.org/sections/health-shots/2018/07/17/
629543151/insurers-and-government-are-slow-to-cover-expensive-car-t-cancer-therapy

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

editing embryo DNA / genome editing        USA / UK

 

edit DNA in human embryos

to fix a disease gene

 

http://www.npr.org/sections/health-shots/2017/09/20/
551779921/editing-embryo-dna-yields-clues-about-early-human-development

 

http://www.npr.org/sections/health-shots/2017/08/18/
543769759/a-first-look-inside-the-lab-where-scientists-are-editing-dna-in-human-embryos

 

https://www.theguardian.com/commentisfree/2017/aug/03/
gene-editing-mitochondrial-replacement-therapy-designer-babies

 

https://www.nytimes.com/2017/08/02/
science/gene-editing-human-embryos.html

 

http://www.npr.org/sections/health-shots/2017/08/02/
540975224/scientists-precisely-edit-dna-in-human-embryos-to-fix-a-disease-gene

 

https://www.theguardian.com/science/2017/aug/02/
deadly-gene-mutations-removed-from-human-embryos-in-landmark-study

 

 

 

 

 

 

 

 

 

 

 

 

 

 

edit genes to treat disease        USA

http://www.npr.org/sections/health-shots/2017/08/10/
542659066/people-back-editing-genes-to-treat-disease-but-are-wary-of-inheritable-changes

 

 

 

 

change traits        USA

http://www.npr.org/sections/health-shots/2017/08/10/
542659066/people-back-editing-genes-to-treat-disease-but-are-wary-of-inheritable-changes

 

 

 

 

edit genes of human embryos        USA

http://www.nytimes.com/2015/04/24/
health/chinese-scientists-edit-genes-of-human-embryos-raising-concerns.html

 

 

 

 

edit DNA of healthy human embryos        USA

http://www.npr.org/sections/health-shots/2016/09/22/
494591738/breaking-taboo-swedish-scientist-seeks-to-edit-dna-of-healthy-human-embryos

 

 

 

 

edit DNA In human embryos        USA

http://www.npr.org/sections/health-shots/2015/09/18/
441408880/british-scientists-seek-permission-to-edit-dna-in-human-embryos

 

 

 

 

genetic engineering        USA

http://www.npr.org/sections/health-shots/2016/06/08/
481234642/new-genetic-engineering-method-called-promising-and-perilous

 

http://www.npr.org/sections/health-shots/2015/11/05/
451216596/powerful-gene-drive-can-quickly-change-an-entire-species

 

 

 

 

genetic enhancements        UK

https://www.theguardian.com/commentisfree/2016/aug/28/
ideology-liberal-democracy-technology-bioscience-yuval-harari-artificial-intelligence

 

 

 

 

genome editing

Ethics of Genome Editing.

Questions on Medical Treatments and the Impact on Future Generations

video - UNESCO- 20 October 2020

https://www.youtube.com/watch?v=a2wd8jqW5fM

 

 

 

 

Genome editing:

how to modify genetic faults – and the human germline        UK        2 September 2015

 

Is it time for a debate

on whether there are

any circumstances

where there is an ethical case

for ‘editing’ human embryos?

http://www.theguardian.com/science/2015/sep/02/
genome-editing-how-to-modify-genetic-faults-and-the-human-germline

 

 

 

 

genetically modified / engineered immune cells > 'living drugs'        USA

https://www.npr.org/sections/health-shots/2018/09/14/
646754993/update-a-young-mans-experiment-with-a-living-drug-for-leukemia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

gene editing        UK

 

https://www.theguardian.com/commentisfree/2017/aug/03/
gene-editing-mitochondrial-replacement-therapy-designer-babies

 

 

 

 

 

 

 

gene editing        USA

 

https://www.nytimes.com/2018/07/11/
health/gene-editing-cancer.html

 

https://www.npr.org/sections/health-shots/2017/12/20/
571208704/scientists-use-gene-editing-to-prevents-a-form-of-deafness-in-mice

 

http://www.npr.org/sections/health-shots/2017/01/01/
507244429/unexpected-risks-found-in-editing-genes-to-prevent-inherited-disorders

 

 

 

 

http://www.npr.org/sections/health-shots/2016/05/18/
478212837/in-search-for-cures-scientists-create-embryos-that-are-both-animal-and-human

 

http://www.nytimes.com/2016/01/01/
science/gene-therapy-muscular-dystrophy.html

 

 

 

 

http://www.nytimes.com/2015/11/15/
magazine/the-crispr-quandary.html

 

 

 

 

http://www.npr.org/sections/health-shots/2014/10/13/
354934248/in-hopes-of-fixing-faulty-genes-one-scientist-starts-with-the-basics

 

 

 

 

 

 

 

a way to efficiently and precisely remove genes

from white blood cells of the immune system

and to insert beneficial replacements        USA

 

https://www.nytimes.com/2018/07/11/
health/gene-editing-cancer.html

 

 

 

 

 

 

 

gene editing in animals        USA

 

http://www.nytimes.com/2015/11/27/us/
2015-11-27-us-animal-gene-editing.html

 

 

 

 

 

 

 

editing human genes        USA

 

http://www.npr.org/sections/health-shots/2015/12/03/
458212497/scientists-debate-how-far-to-go-in-editing-human-genes

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

designer baby        USA

 

https://www.npr.org/sections/health-shots/2019/05/02/
719665841/why-making-a-designer-baby-would-be-easier-said-than-done

 

https://www.npr.org/sections/health-shots/2019/02/01/
689623550/new-u-s-experiments-aim-to-create-gene-edited-human-embryos

 

https://www.nytimes.com/2018/06/10/
us/11retro-baby-genetics.html

 

http://www.npr.org/sections/health-shots/2017/02/14/
514580162/scientific-panel-says-editing-heritable-human-genes-could-be-ok-in-the-future

 

 

 

 

 

 

 

designer babies / making embryos in a lab        USA

 

http://www.npr.org/sections/health-shots/2016/06/16/
482189322/will-baby-making-move-from-the-bedroom-to-the-lab

 

http://www.npr.org/sections/health-shots/2015/12/03/
458212497/scientists-debate-how-far-to-go-in-editing-human-genes

 

 

 

 

 

 

 

better babies        USA

 

https://www.nytimes.com/2018/06/10/us/11
retro-baby-genetics.html

 

 

 

 

 

 

 

baby with 3 genetic parents        USA

 

Last fall,

the New York-based reproductive

endocrinologist John Zhang

made headlines when he reported

the birth of the world's

first "three-parent" baby

— a healthy boy

carrying the blended DNA

of the birth mother, her husband

and an unrelated female donor.

 

The technique,

called mitochondrial replacement therapy,

allowed the 36-year-old mother

to bypass a defect in her own genome

that had led, twice before,

to children born with Leigh syndrome,

a devastating neurological disorder

that typically culminates in death

before age 3.

 

While heralded in many circles

as a breakthrough,

the news triggered

numerous ethical

and scientific questions,

many of which remained

unanswered at the time.

 

Last week,

Zhang and his colleagues

at the New Hope Fertility Center

provided some answers

— and raised yet more concerns.

 

http://www.npr.org/sections/health-shots/2017/04/08/
523020895/a-baby-with-3-genetic-parents-seems-healthy-but-questions-remain

 

 

 

 

 

 

 

 

 

 

 

 

 

 

gene therapy        UK

 

http://www.guardian.co.uk/science/2013/apr/30/
gene-therapy-trials-heart-patients

 

http://www.guardian.co.uk/science/2000/jun/26/
genetics.drugs

 

 

 

 

 

 

 

gene therapy        USA

 

https://www.npr.org/sections/health-shots/2020/07/27/
893289171/a-boy-with-muscular-dystrophy-was-headed-for-a-wheelchair-then-gene-therapy-arri

 

https://www.npr.org/sections/health-shots/2019/04/17/
714121698/gene-therapy-advances-to-better-treat-bubble-boy-disease

 

https://www.npr.org/sections/health-shots/2018/04/18/
602914728/gene-therapy-for-inherited-blood-disorder-reduced-transfusions

 

http://www.npr.org/sections/health-shots/2015/07/08/
421204204/genetic-tweaks-are-restoring-hearing-in-animals-raising-hopes-for-people

 

https://www.npr.org/sections/health-shots/2013/12/07/
249335960/gene-therapy-keeps-bubble-boy-disease-at-bay-in-8-children

 

 

 

 

 

 

 

pioneering treatment > replacement gene        UK

 

http://www.guardian.co.uk/science/2013/apr/30/
gene-therapy-trials-heart-patients

 

 

 

 

 

 

 

gene therapy > Parkinson's disease        UK

 

http://www.theguardian.com/uk/2006/oct/18/
genetics.science 

 

 

 

 

 

 

 

 

 

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