Vocapedia > Health > Genetics > Gene editing
How to defeat malaria
The Economist 25 April 2019
How to defeat malaria
Video The Economist 25 April 2019
Malaria still kills around 400,000 people a year.
Efforts to eradicate the disease have stalled because of drug resistance
—but pioneering gene-editing technology might offer a new solution
the biggest revolution in gene editing
G 28 March 2019
Crispr-Cas9 explained: the biggest revolution in gene editing
Video The Guardian 28 March 2019
Professor Jennifer Doudna,
one the pioneers of Crispr-Cas9 gene editing
explains how this important discovery
enables precise changes to our DNA,
which can be used to correct mutations
that cause genetic disease
and completely eradicate it from a germline.
Doudna raises the 4 key issues of debate
around this revolutionary discovery
and suggests what will have the most immediate impact.
Biologist Explains One Concept
in 5 Levels of Difficulty - CRISPR
WIRED 24 May 2017
Biologist Explains One Concept in 5 Levels of Difficulty
Video CRISPR | WIRED 24 May 2017
biotechnology breakthrough >
gene-editing technology > Crispr-Cas9 UK / USA
CRISPR, which stands for
Clustered Regularly Interspaced Short Palindromic Repeats,
is the basis for a revolutionary
that allows researchers to make
very precise modifications to DNA.
The CRISPR-cas9 technology
to make precise edits in DNA,
and that ability could lead
to whole new medical therapies,
and even new crop varieties.
While everyone welcomes
as a strategy to treat disease,
many scientists are worried
that it could also be used
to alter genes in human embryos,
sperm or eggs
in ways that can be passed
from generation to generation.
The prospect raises fears
of a dystopian future
in which scientists create
an elite population
of designer babies
with enhanced intelligence,
beauty or other traits.
gene-editing technology > Crispr-Cas9 > agriculture, farming
CRISPR > blind patients > restore vision USA
modify DNA > gene-editing tool > CRISPR > patients with vision loss see color again USA
CRISPR gene-editing tool USA
a CRISPR gene-editing breakthrough USA
It's called CRISPR-Cas9.
And the Cas9 part is an enzyme.
And enzymes are basically things that cut.
And it's a scalpel.
It's a molecular scissors.
So you put those two things together.
You program CRISPR to go where you want.
And when it gets there,
it cuts the very pieces of DNA you want cut.
It's remarkably precise.
It works with great efficiency.
There are - it is not 100 percent perfect.
We can talk about that.
But it's more efficient and more successful
than any such tool there had ever been
or any that anyone had envisioned.
gene-editing technology > gene-edited babies USA
create genetically modified babies using CRISPR USA
create gene-edited human embryos USA
Jennifer A. Doudna
at the University of California, Berkeley
(who) helped make one
of the most monumental
discoveries in biology:
a relatively easy way
to alter any organism’s DNA,
just as a computer user
can edit a word in a document.
has turned Dr. Doudna
(the first syllable rhymes with loud)
into a celebrity of sorts,
the recipient of numerous
accolades and prizes.
The so-called Crispr-Cas9
genome editing technique
is already widely used
in laboratory studies,
and scientists hope
it may one day help
rewrite flawed genes in people,
opening tremendous new possibilities
for treating, even curing, diseases.
editing the human genome / genome editing
is a powerful procedure
that has already been a game-changer
in helping scientists to understand
the roles of genes
in health and diseases.
It coopts the natural immune
defences of bacteria
to create what is often described
as “molecular scissors”.
These can cut out, but also replace,
strands of DNA with great precision.
It is possible to change
single letters of the DNA code.
https://www.youtube.com/watch?v=-sU2HrmZ-7s - 18 August 2015
Related > Anglonautes > Vocapedia
genetically modified (GM) food, edited food
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lifestyle / health > exercise,