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Vocapedia > Health > Microbes

 

Bacteria, Viruses, Coronaviruses, Rhinoviruses

 

Vaccines, Vaccination

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pandemics        UK

 

https://www.theguardian.com/society/ng-interactive/2020/apr/29/
how-humans-have-reacted-to-pandemics-through-history-a-visual-guide

 

 

 

 

 

 

 

antiviral drugs        USA

 

https://www.nytimes.com/interactive/2020/03/11/
science/how-coronavirus-hijacks-your-cells.html

 

 

 

 

 

 

 

vaccination programmes        UK

 

https://www.theguardian.com/global-development/2020/apr/27/
a-rise-in-deaths-from-preventable-diseases-must-not-be-part-of-covid-19s-legacy

 

 

 

 

 

 

 

 

 

 

 

 

 

 

vaccine, vaccination        FR / USA

 

https://www.mediapart.fr/journal/dossier/culture-idees/
une-histoire-geopolitique-des-vaccins

 

 

https://www.nytimes.com/2022/01/15/
health/mrna-vaccine.html

 

 

 

 

https://www.nytimes.com/2021/01/25/
science/mass-vaccine-drives.html

 

https://www.nytimes.com/2021/01/11/
well/family/an-appreciation-for-vaccines-and-how-far-they-have-come.html

 

 

 

 

https://www.nytimes.com/2020/11/17/
opinion/vaccine-coronavirus.html

 

https://www.npr.org/2020/09/04/
909669962/why-are-so-many-americans-hesitant-to-get-a-covid-19-vaccine

 

https://www.npr.org/2020/07/01/
885906633/the-mask-debate-is-over-fauci-on-mandates-vaccine-skepticism

 

https://www.npr.org/2020/06/04/
869798010/the-very-first-vaccine

 

https://www.nytimes.com/2020/04/27/
well/live/coronavirus-as-a-reminder-of-the-urgency-of-getting-your-vaccines.html

 

 

 

 

https://www.npr.org/sections/health-shots/2019/05/20/
724468630/the-other-reasons-kids-arent-getting-vaccinations-poverty-and-health-care-access

 

https://www.npr.org/sections/goatsandsoda/2019/05/03/
719037789/botched-vaccine-launch-has-deadly-repercussions

 

https://www.npr.org/2019/05/01/
719012022/outbreak

 

https://www.npr.org/2019/03/08/
701553920/unvaccinated-boy-6-spent-57-days-in-the-hospital-with-tetanus

 

https://www.npr.org/2019/03/07/
701358833/facebook-vows-to-quash-anti-vaccine-misinformation

 

https://www.npr.org/2019/03/06/
700617424/18-year-old-testifies-about-getting-vaccinated-despite-mothers-anti-vaccine-beli

 

https://www.npr.org/sections/health-shots/2019/02/20/
696259456/a-parent-to-parent-campaign-to-get-vaccine-rates-up

 

https://www.npr.org/sections/health-shots/2019/02/13/
694449743/medical-anthropologist-explores-vaccine-hesitancy

 

 

 

 

 

 

 

mRNA Vaccines        USA

 

https://www.nytimes.com/2022/01/15/
health/mrna-vaccine.html

 

 

 

 

 

 

 

AstraZeneca

buys US vaccine company in $1.1bn deal        UK

Britain’s biggest drugmaker

acquires Seattle-based firm Icosavax,

expanding vaccine

and immune therapy business

https://www.theguardian.com/business/2023/dec/12/
astrazeneca-buys-us-vaccine-company-icosavax-seattle

 

https://www.theguardian.com/business/
astrazeneca

 

https://www.theguardian.com/business/2023/dec/12/
astrazeneca-buys-us-vaccine-company-icosavax-seattle

 

 

 

 

 

 

 

vaccine drives        USA

 

https://www.nytimes.com/2021/01/25/
science/mass-vaccine-drives.html

 

 

 

 

 

 

 

 Bacille Calmette Guerin    BCG

BCG vaccine        UK

 

The BCG vaccine

protects against tuberculosis,

which is also known as TB.

 

TB is a serious infection

that affects the lungs

and sometimes other parts of the body,

such as the bones, joints and kidneys.

It can also cause meningitis.

https://www.nhs.uk/conditions/vaccinations/bcg-tuberculosis-tb-vaccine/

 

https://www.nhs.uk/conditions/vaccinations/
bcg-tuberculosis-tb-vaccine/

 

 

https://www.theguardian.com/science/audio/2020/apr/30/
covid-19-what-has-the-bcg-vaccine-got-to-do-with-it-podcast

 

 

 

 

 

 

 

DTP vaccine        USA

 

vaccine against

Diphtheria,

Pertussis,

better known as whooping cough,

and Tetanus

 

https://www.nytimes.com/2021/01/11/
well/family/an-appreciation-for-vaccines-and-how-far-they-have-come

 

 

 

 

 

 

 

vaccine, vaccination against variola virus        USA

 

https://www.cdc.gov/smallpox/history/history.html

 

 

 

 

 

 

 

cold storage        USA

 

https://www.npr.org/sections/health-shots/2020/11/17/
935563377/why-does-pfizers-covid-19-vaccine-need-
to-be-kept-colder-than-antarctica

 

 

 

 

 

 

 

vaccinated        USA

 

https://www.npr.org/2019/03/08/
701553920/unvaccinated-boy-6-
spent-57-days-in-the-hospital-with-tetanus

 

 

 

 

 

 

 

 

 

 

 

 

 

 

vaccine skepticism        USA

 

https://www.npr.org/2020/07/01/
885906633/the-mask-debate-is-over-fauci-on-mandates-vaccine-skepticism

 

 

 

 

 

 

 

anti-vaccine        USA

 

https://www.npr.org/2020/07/01/
885906633/the-mask-debate-is-over-fauci-on-mandates-vaccine-skepticism

 

 

 

 

https://www.npr.org/2019/03/07/
701358833/facebook-vows-to-quash-anti-vaccine-misinformation

 

https://www.npr.org/2019/03/06/
700617424/18-year-old-testifies-about-getting-vaccinated-despite-mothers-anti-vaccine-beli

 

 

 

 

 

 

 

anti-science        USA

 

https://www.npr.org/2020/07/01/
885906633/the-mask-debate-is-over-fauci-on-mandates-vaccine-skepticism

 

 

 

 

 

 

 

 

 

 

 

 

 

 

coronaviruses        UK

 

https://www.theguardian.com/news/audio/2020/may/20/
the-scientific-race-to-understand-covid-19-podcast

 

 

 

 

 

 

 

2012 > viruses > coronaviruses

Middle East respiratory syndrome coronavirus

(MERS-CoV)

 

Middle East Respiratory Syndrome (MERS)

is an illness caused by a virus

(more specifically, a coronavirus)

called Middle East Respiratory Syndrome Coronavirus

(MERS-CoV).

 

Most MERS patients

developed severe respiratory illness

with symptoms of fever,

cough and shortness of breath.

 

About 3 or 4 out of every 10 patients

reported with MERS have died.

 

 

 

All cases

are linked to the Arabian Peninsula

 

Health officials first reported the disease

in Saudi Arabia in September 2012.

 

Through retrospective

(backward-looking) investigations,

they later identified

that the first known cases of MERS

occurred in Jordan in April 2012.

 

So far, all cases of MERS

have been linked through travel to,

or residence in,

countries in and near the Arabian Peninsula.

 

The largest known outbreak of MERS

outside the Arabian Peninsula

occurred in the Republic of Korea in 2015.

 

The outbreak was associated

with a traveler returning

from the Arabian Peninsula.

 

 

 

People with MERS can spread it to others

 

MERS-CoV has spread

from ill people to others

through close contact,

such as caring for

or living with an infected person.

 

MERS can affect anyone.

MERS patients have ranged in age

from younger than 1 to 99 years old.

- 20 May 2020

https://www.cdc.gov/coronavirus/mers/

 

 

 

 

 

 

 

2003 > viruses > coronaviruses

severe acute respiratory syndrome coronavirus

(SARS-CoV)

 

Severe acute respiratory syndrome (SARS)

is a viral respiratory illness

caused by a coronavirus called

SARS-associated coronavirus (SARS-CoV).

 

SARS was first reported in Asia

in February 2003.

 

The illness spread

to more than two dozen countries

in North America, South America,

Europe, and Asia

before the SARS global outbreak of 2003

was contained.

 

Since 2004,

there have not been any known cases of SARS

reported anywhere in the world.

- 20 May 2020

https://www.cdc.gov/sars/index.html

 

 

 

 

 

 

 

viruses > RNA virus > common cold virus

 

Rhinoviruses are a major cause

of the common cold and may contribute

to about half of asthma flare-ups.

 

Researchers

have now completed

sequencing the genomes

of all the known rhinovirus types,

setting the stage

for the development

of medications and vaccines

to combat the viruses.

 

The cold

is the most common illness known,

bringing the sneezing, scratchy throat

and runny nose

that we're all familiar with.

 

People in the United States

have an estimated 1 billion colds

each year.

 

More than 200 different viruses

are known to cause

the symptoms of the common cold.

 

An estimated 30-35% of all adult colds

are caused by rhinoviruses.

 

In people with asthma,

particularly children,

rhinovirus infections

are also frequently associated

with flare-ups.

 

Scientists had previously identified

99 distinct rhinovirus types.

 

Recently, however,

a number of unknown types

were detected in patients

with severe flu-like illnesses.

 

(...)

 

Rhinoviruses contain

all their genetic information

on a single strand of RNA

(a molecule related to DNA).

- last updated April 13, 2009

https://www.nih.gov/news-events/
nih-research-matters/understanding-common-cold-virus

 

 

 

Colds are caused by viruses

and easily spread to other people.

 

You're infectious

until all your symptoms have gone.

 

This usually takes a week or 2.

Colds are spread by germs

from coughs and sneezes,

which can live on hands and surfaces

for 24 hours.

 

 

 

To reduce

the risk of spreading a cold:

 

wash your hands often

with warm water and soap

use tissues to trap germs

when you cough or sneeze

bin used tissues

as quickly as possible

 

 

 

How to prevent catching a cold

 

A person with a cold can start spreading it

from a few days before their symptoms begin

until the symptoms have finished.

 

 

 

The best ways

to avoid catching a cold are:

washing your hands

with warm water and soap

 

not sharing towels

or household items (like cups)

with someone who has a cold

 

not touching your eyes or nose

in case you have come

into contact with the virus

– it can infect the body this way

 

staying fit and healthy

 

The flu vaccine helps prevent flu

but not colds.

- 20 May 2020

https://www.nhs.uk/conditions/common-cold/

 

 

https://www.nhs.uk/conditions/common-cold/

 

https://www.nih.gov/news-events/nih-research-matters/
understanding-common-cold-virus

 

https://en.wikipedia.org/wiki/Common_cold

 

https://en.wikipedia.org/wiki/RNA_virus

 

 

 

 

 

 

 

 

 

 

 

 

 

 

varicella zoster virus > shingles > vaccine    UK / USA

 

Shingles,

also known as herpes zoster,

is an infection of a nerve

and the skin around it.

 

It is caused

by the varicella-zoster virus,

which also causes chickenpox.

 

Shingles usually affects

a specific area

on one side of the body

and does not cross

over the midline of the body

(an imaginary line

running from between your eyes

down past the belly button).

 

The main symptom is a painful rash

that develops into itchy blisters

that contain particles of the virus.

 

An episode of shingles

typically lasts

around two to four weeks,

although around one in five people

go on to develop nerve pain

called postherpetic neuralgia

in the affected area of skin.

http://www.nhs.uk/conditions/shingles/Pages/Introduction.aspx

 

https://www.nhs.uk/conditions/shingles/

 

 

https://www.npr.org/sections/health-shots/2018/03/20/
594956495/shingles-is-nasty-and-the-new-vaccine-works-well-why-do-adults-avoid-shots

 

http://www.npr.org/sections/health-shots/2015/07/13/
421570746/engineering-a-shingles-vaccine-that-doesnt-wimp-out-over-time

 

 

 

 

 

 

 

 

 

 

 

 

 

 

measles vaccine        USA

 

http://www.npr.org/blogs/goatsandsoda/2015/05/07/
404963436/scientists-crack-a-50-year-old-mystery-about-the-measles-vaccine

 

 

 

 

 

 

 

German measles / rubella

causes only a mild illness in children,

with a rash and sometimes a fever.

 

But when pregnant women

catch rubella,

their babies can develop

serious birth defects,

like heart problems, blindness

and learning disabilities.

 

The virus can also trigger miscarriages

early in a pregnancy.        USA

http://www.npr.org/blogs/goatsandsoda/2015/04/30/
403388700/western-hemisphere-wipes-out-its-third-virus

 

 

 

In the 1964-1965 rubella pandemic,

an estimated 50,000 pregnant women

in the United States

were exposed to rubella in pregnancy,

resulting in miscarriages, stillbirths,

and 20,000 babies born

with congenital rubella syndrome,

which caused blindness, deafness,

brain and heart damage.

 

At the height of the pandemic,

an estimated 1 out of every 100 babies

born in Philadelphia was afflicted.

 

A vaccine for rubella

was introduced in the 1970s,

so parents no longer

have to live in fear.

http://www.npr.org/blogs/goatsandsoda/2015/04/30/
403388700/western-hemisphere-wipes-out-its-third-virus

 

 

https://www.nytimes.com/2018/11/12/
well/family/veterans-day-war-brooklyn-measles-outbreak-mumps-immunizations.html

 

https://www.npr.org/sections/thetwo-way/2018/02/20/
587350782/europe-saw-4-fold-increase-in-measles-cases-in-2017

 

http://www.npr.org/sections/health-shots/2016/01/30/
464899067/before-zika-virus-rubella-was-a-pregnant-womans-nightmare

 

http://www.npr.org/blogs/goatsandsoda/2015/04/30/
403388700/western-hemisphere-wipes-out-its-third-virus

 

 

 

 

 

 

 

human papillomavirus    HPV

 

the cause of most cervical cancer        UK / USA

 

https://www.theguardian.com/society/hpv-vaccine

 

 

https://www.theguardian.com/society/2017/jul/19/
hpv-vaccine-anger-decision-not-extend-nhs-scheme-boys-cancer

 

http://www.npr.org/sections/health-shots/2016/02/01/
465160937/cdc-endorses-a-more-effective-hpv-vaccine-to-prevent-cancer

 

http://www.npr.org/blogs/health/2014/02/03/
271074253/hpv-vaccine-doesnt-promote-riskier-sexual-behavior-in-teens

 

http://www.npr.org/blogs/health/2013/11/07/
243731105/doctors-slow-to-embrace-recommended-hpv-testing

http://www.npr.org/blogs/health/2013/11/07/
243731105/doctors-slow-to-embrace-recommended-hpv-testing

http://www.nytimes.com/2013/07/19/
health/hpv-vaccine-found-to-help-with-cancers-of-throat.html

http://www.guardian.co.uk/society/2013/jun/04/
hpv-vaccine-health-michael-douglas

http://www.nytimes.com/2013/06/04/
health/throat-cancer-link-to-oral-sex-gains-credence.html

http://www.guardian.co.uk/news/datablog/2013/jun/02/
michael-douglas-oral-sex-cancer-facts

 

http://www.guardian.co.uk/society/2010/oct/17/
oral-sex-cancer-documentary-jaime-winstone

 

 

 

 

 

 

 

 

 

 

 

 

 

 

meningitis        USA

 

http://www.npr.org/blogs/health/2013/12/12/
250417012/why-meningitis-that-hit-princeton-
is-hard-to-beat-with-vaccines

 

 

 

 

 

 

 

 

 

 

 

 

 

 

immunization        USA

 

https://www.nytimes.com/2020/04/27/
well/live/coronavirus-as-a-reminder-of-the-urgency-of-getting-your-vaccines.html

 

 

 

 

 

 

 

 

 

Corpus of news articles

 

Health > Microbes >

 

Bacteria, Viruses, Coronaviruses, Rhinoviruses >

 

Vaccines, Vaccination
 

 

 

The Real Threat of ‘Contagion’

 

September 11, 2011

The New York Times

By W. IAN LIPKIN

 

I ADMIT I was wary when I was approached, late in 2008, about working on a movie with the director Steven Soderbergh about a flulike pandemic. It seemed that every few years a filmmaker imagined a world in which a virus transformed humans into flesh-eating zombies, or scientists discovered and delivered the cure for a lethal infectious disease in an impossibly short period of time.

Moviegoers might find fantasies like these entertaining, but for a microbe hunter like me, who spends his days trying to identify the viruses that cause dangerous diseases, the truth about the potential of global outbreaks is gripping enough.

Then I discovered that Mr. Soderbergh and the screenwriter on the project, Scott Z. Burns, agreed with me. They were determined to make a movie — “Contagion,” which opened this weekend — that didn’t distort reality but did convey the risks that we all face from emerging infectious diseases.

Those risks are very real — and are increasing drastically. More than three-quarters of all emerging infectious diseases originate when microbes jump from wildlife to humans. Our vulnerability to such diseases has been heightened by the growth in international travel and the globalization of food production. In addition, deforestation and urbanization continue to displace wildlife, increasing the probability that wild creatures will come in contact with domesticated animals and humans.

When I was a kid, the launching of Sputnik made us aware that the United States was falling behind the Soviet Union in the race for space. Now all of us are in a battle that is potentially devastating, only it is not against another country, but against microbes. Could a movie like “Contagion” be an effective vehicle for sounding the alarm?

In the hope that it would, I signed on as a paid technical consultant on the film. The first order of business was a casting call for the virus itself. Together with my team at the Center for Infection and Immunity at Columbia University’s Mailman School of Public Health, I devised the imaginary virus that wreaks havoc in the film. We used as our inspiration the Nipah virus, which in Malaysia in the late 1990s jumped from bats to pigs to humans, causing respiratory disease and encephalitis and resulting in more than 100 deaths before it was contained by quarantine.

My team built a 3-D model of our virus and then worked out how it would spread and evolve, how it would be discovered, how the public health and medical communities and governments would respond regionally and internationally, how vaccines would be developed and distributed. In the film, it takes the lives of millions of people.

Is this fiction? Yes. Is it real? Absolutely. During the SARS outbreak of 2003, the first pandemic of the 21st century, I flew to Beijing at the invitation of the Chinese government to help address the situation there. My memories of deserted streets, food and supply shortages, and political instability are reflected in scenes in “Contagion.” I hope the public and our lawmakers will see the movie as a cautionary tale. Pandemics have happened before. And they will happen again.

What can we do to prepare ourselves? A presidential directive in 2007 led to the establishment of the National Biosurveillance Advisory Subcommittee, at the Centers for Disease Control and Prevention, to assess our biosurveillance capabilities and make recommendations for improving detection, prevention and management of biohazards. The subcommittee, which includes representatives from federal, state and local agencies, academia and industry (and on which I serve as co-chairman), has issued reports that provide a road map for steps we have to take to protect our future.

First, we need to recognize that our public health system is underfinanced and overwhelmed. We must invest in sensitive, inexpensive diagnostic tests and better ways of manufacturing and distributing drugs and vaccines. Although new technology now allows us to design many vaccines in days, manufacturing strategies for influenza vaccines have not changed in decades. Some experts will say that the time frame within which “Contagion” introduces the film’s MEV-1 vaccine is unrealistically short; however, it need not be so. We can and must reduce the several months required to create and test a vaccine before beginning large-scale production and distribution.

Second, more and better coordination is needed among many local, federal and international agencies. Joint effort is required to monitor human, animal and environmental health, optimize electronic health records, mine nontraditional data sources like the Internet for early signs of outbreaks and invest in a state-of-the-art work force.

“Contagion” makes the case that scientists and public health professionals who put themselves on the line to fight infectious diseases are heroes. I hope that, like Sputnik, it will inspire young people to pursue these careers and help the rest of the country understand the importance of these efforts. It is what the world urgently needs.

 

W. Ian Lipkin is a professor of epidemiology

and a professor of neurology and pathology

at Columbia University.

The Real Threat of ‘Contagion’,
NYT,
11.9.2011,
http://www.nytimes.com/2011/09/12/
opinion/the-real-threat-of-contagion.html

 

 

 

 

 

 

 

 

 

Related > Anglonautes > Vocapedia

 

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health, medicine, drugs,

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USA > prescription opioid painkillers

 

 

lifestyle / health > exercise,

smoking / tobacco, vaping,

drinking / alcohol,

diet, obesity

 

 

 

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